Papilary thyroid carcinoma book : Chapter 14

There has been a worldwide increase in the incidence of thyroid cancer in recent years.

Papillary thyroid carcinoma is the most common neoplasm in the thyroid gland and affects predominately females. The aims of the book are to present status and management protocols with the objective of identifying proper guidelines and materials for research related to the neoplasm. The different protocols provided will help to understand the pathogenesis as well as improvement of the care of patients with papillary thyroid carcinoma. The target audience of the book includes diverse groups of medical science students, medical students, academics, researchers, and multi-disciplinary clinical teams in management of thyroid cancer such as pathologists, surgeons, radiation oncologists, and endocrinologists.

Chapter 1 introduces the epidemiology, genomic, and clinical characteristics of patients with papillary thyroid carcinoma. This chapter guides the readers to explore the other chapters of the book.
Chapters 2, 3, 4, and 5 illustrate the diagnostic approaches (ultrasonic examination and fine needle aspiration) and initial surgical managements (thyroidectomy and neck lymph node dissection) for patients with papillary thyroid carcinoma.
Chapters 6, 7, and 8 detail the guidelines for macroscopic examination, microscopic examination, and

pathological staging of papillary thyroid carcinoma.
Chapters 9, 10, 11, and 12 highlight different molecular approaches to the cancer which include siRNA, non-coding RNA, single nucleotide polymorphism, and detection of BRAF mutation, the most important mutation noted in papillary thyroid carcinoma.
Chapters 13 and 14 identify the most used pathology laboratory approaches to study papillary thyroid carcinoma, including immunohistochemistry and whole slide imaging. Finally, it is important to be aware of the radiology oncology treatment protocols of thyroid carcinoma as presented in Chapters 15, 16, and 17.

By using this book, readers will understand the most updated information on different aspects of the processes, cost, and resources available for the research and management of patients with papillary thyroid carcinoma. Increasing awareness and promoting research in this area will certainly translate to improving the management of papillary thyroid carcinoma.

I thank all the authors for their invaluable contributions.

Gold Coast, QLD, Australia Alfred K. Lam